Molecular Weight: 136.11 Hypoxanthine is a naturally occurring purine derivative.
Hypoxanthine is a naturally occurring purine derivative. It is
occasionally found as a constituent of nucleic acids, where it is
present in the anticodon of tRNA in the form of its nucleoside inosine.
It has a tautomer known as 6-hydroxypurine. Hypoxanthine is a necessary
additive in certain cell, bacteria, and parasite cultures as a substrate
and nitrogen source.
Protocol(Only for Reference)
Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
|Body Surface Area (m2)||0.6||0.5||0.24||0.15||0.05||0.025||0.02||0.007|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
|Rat dose (mg/kg) = mouse dose (22.4 mg/kg) ×||mouse Km(3)||= 11.2 mg/kg|
|Molecular Weight (MW)||136.11|
|Storage||3 years -20℃Powder|
|6 months-80℃in solvent (DMSO, water, etc.)|
|Solubility (25°C) *||In vitro||DMSO||0.4 mg/mL (2.93 mM)|
|Water||<1 mg/mL (|
|Ethanol||<1 mg/mL (|
| * <1 mg/ml means slightly soluble or insoluble. |
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
|Chemical Name||6H-Purin-6-one, 1,9-dihydro-|
Molecular Weight Calculator
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