Molecular Weight: 287.32 Rutaecarpine is an indolopyridoquinazolinone alkaloid isolated from Evodia rutaecarpa and related herbs.
Rutaecarpine is an indolopyridoquinazolinone alkaloid isolated from
Evodia rutaecarpa and related herbs, which has shown a variety of
intriguing biological properties such as anti-thrombotic, anticancer,
anti-inflammatory and analgesic, anti-obesity and thermoregulatory,
vasorelaxing activity, as well as effects on the cardiovascular and
Protocol(Only for Reference)
Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
|Body Surface Area (m2)||0.6||0.5||0.24||0.15||0.05||0.025||0.02||0.007|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
|Rat dose (mg/kg) = mouse dose (22.4 mg/kg) ×||mouse Km(3)||= 11.2 mg/kg|
|Molecular Weight (MW)||287.32|
|Storage||3 years -20℃Powder|
|6 months-80℃in solvent (DMSO, water, etc.)|
|Solubility (25°C) *||In vitro||DMSO||24 mg/mL (83.53 mM)|
|Water||<1 mg/mL (|
|Ethanol||<1 mg/mL (|
|Chemical Name||Indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one, 8,13-dihydro-|
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