Risedronate Sodium 115436-72-1
Product Description
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Risedronate Sodium
Risedronate Sodium Chemical Structure
Molecular Weight: 305.09 Risedronate Sodium is a bisphosphonate used to strengthen bone, treat or prevent osteoporosis, and treat Paget's disease of bone.
Biological Activity
Risedronate sodium is a bisphosphonate used to strengthen bone, treat or prevent osteoporosis, and treat Paget's disease of bone.
Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
Chemical Information
Contact us if you need more details on Risedronate Sodium. We are ready to answer your questions on packaging, logistics, certification or any other aspects about 115436-72-1、115436-72-1 Risedronate Sodium. If these products fail to match your need, please contact us and we would like to provide relevant information.
Risedronate Sodium
Risedronate Sodium Chemical Structure
Molecular Weight: 305.09 Risedronate Sodium is a bisphosphonate used to strengthen bone, treat or prevent osteoporosis, and treat Paget's disease of bone.
Biological Activity
Risedronate sodium is a bisphosphonate used to strengthen bone, treat or prevent osteoporosis, and treat Paget's disease of bone.
Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
| Species | Baboon | Dog | Monkey | Rabbit | Guinea pig | Rat | Hamster | Mouse |
| Weight (kg) | 12 | 10 | 3 | 1.8 | 0.4 | 0.15 | 0.08 | 0.02 |
| Body Surface Area (m2) | 0.6 | 0.5 | 0.24 | 0.15 | 0.05 | 0.025 | 0.02 | 0.007 |
| Km factor | 20 | 20 | 12 | 12 | 8 | 6 | 5 | 3 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
| Rat dose (mg/kg) = mouse dose (22.4 mg/kg) × | mouse Km(3) | = 11.2 mg/kg |
| rat Km(6) |
Chemical Information
| Molecular Weight (MW) | 305.09 |
|---|---|
| Formula | C7H10NNaO7P2 |
| CAS No. | 115436-72-1 |
| Storage | 3 years -20℃Powder |
|---|---|
| 6 months-80℃in solvent (DMSO, water, etc.) | |
| Synonyms | |
| Solubility (25°C) * | In vitro | DMSO | <1 mg/mL ( |
|---|---|---|---|
| Water | 2 mg/mL (6.55 mM) | ||
| Ethanol | <1 mg/mL ( | ||
| Chemical Name | sodium hydrogen-1-hydroxy-1-phosphono-2-(pyridin-3-yl)ethylphosphonate |
|---|
Contact us if you need more details on Risedronate Sodium. We are ready to answer your questions on packaging, logistics, certification or any other aspects about 115436-72-1、115436-72-1 Risedronate Sodium. If these products fail to match your need, please contact us and we would like to provide relevant information.
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