Gliquidone 33342-05-1

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Molecular Weight:

527.63 Gliquidone is an ATP-sensitive K+ channel antagonist with IC50 of 27.2 nM.

Biological Activity




Gliquidone (6 μg per mouse, i.c.v.) prevents the antinociception
induced by clonidine (0.125 mg/kg, s.c.) and guanabenz (0.30 mg/kg,
s.c.), while a lower dose of gliquidone (3 μg per mouse, i.c.v.) is
ineffective.


Glurenorm (10 mg/kg) given to the diabetic
rats produces significant reductions in blood glucose, nonenzymatic
glycosylation, and total protein in the lenses, and significantly
increases in glutathione levels in the lenses.

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Product Categories : Transmembrane Transporters > Potassium Channel Inhibitor