Ciprofibrate 52214-84-3

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Molecular Weight:

289.15 Ciprofibrate is a peroxisome proliferator-activated receptor agonist.






Biological Activity


Ciprofibrate is a peroxisome proliferator-activated receptor agonist. It was reported that ciprofibrate decreased the levels of plasma triglycerides and total cholesterol as well as low-density lipoprotein cholesterol. Meanwhile, ciprofibrate elevated plasma levels of high-density lipoprotein cholesterol.


The maximum concentration time of ciprofibrate is between one hour and 2.5 hours while the long half life (80 -100 h) permits daily dosing of the drug. In addition, the maximum plasma concentration is between 66 and 88 μg/mL after chronic administration of 100 mg/day of ciprofibrate.


Ciprofibrate belongs to the second generation of fibric acid derivatives which used to treat patients with dyslipidaemias of various types.

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