CCG-1423 285986-88-1

Molecular Weight:454.75 CCG-1423 is a Specific RhoA Pathway Inhibitor, which inhibits SRF-mediated transcription.


Biological Activity


Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)

Species	Baboon	Dog	Monkey	Rabbit	Guinea pig	Rat	Hamster	Mouse
Weight (kg)	12	10	3	1.8	0.4	0.15	0.08	0.02
Body Surface Area (m2)	0.6	0.5	0.24	0.15	0.05	0.025	0.02	0.007
Km factor	20	20	12	12	8	6	5	3

Animal A (mg/kg) = Animal B (mg/kg) multiplied by	Animal B Km
	Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Rat dose (mg/kg) = mouse dose (22.4 mg/kg) ×	mouse Km(3)	= 11.2 mg/kg
	rat Km(6)

Chemical Information

Molecular Weight (MW)	454.75
Formula	C18H13ClF6N2O3
CAS No.	285986-88-1

Storage	3 years -20℃Powder
	6 months-80℃in solvent (DMSO, water, etc.)
Synonyms	N/A

Chemical Name	N-(1-(4-chlorophenylamino)-1-oxopropan-2-yloxy)-3,5-bis(trifluoromethyl)benzamide

Molarity Calculator
Dilution Calculator
Molecular Weight Calculator

Contact us if you need more details on 285986-88-1. We are ready to answer your questions on packaging, logistics, certification or any other aspects about CCG-1423 285986-88-1、285986-88-1 CCG-1423. If these products fail to match your need, please contact us and we would like to provide relevant information.

Product Categories : Cell Cycle > Rho Inhibitor