Fluocinolone Acetonide 67-73-2
Product Description
.cp_wz table {border-top: 1px solid #ccc;border-left:1px solid #ccc; } .cp_wz table td{border-right: 1px solid #ccc; border-bottom: 1px solid #ccc; padding: 5px 0px 0px 5px;} .cp_wz table th {border-right: 1px solid #ccc;border-bottom: 1px solid #ccc; padding: 5px 0px 0px 5px;}
Molecular Weight:
452.4999 Fluocinolone Acetonide is a corticosteroid that binds to the cytosolic glucocorticoid receptor.
Biological Activity
Fluocinolone acetonide(Flucort-N) is a corticosteroid that binds to the cytosolic glucocorticoid receptor. It is a corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching. It is a synthetic hydrocortisone derivative.
After binding the receptor the newly formed receptor-ligand complex translocates itself into the cell nucleus, where it binds to many glucocorticoid response elements (GRE) in the promoter region of the target genes.
The DNA bound receptor then interacts with basic transcription factors, causing the increase in expression of specific target genes. The anti-inflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory Proteins which, through inhibition arachidonic acid, control the biosynthesis of Prostaglandins and leukotrienes.
Contact us if you need more details on 67-73-2. We are ready to answer your questions on packaging, logistics, certification or any other aspects about Fluocinolone Acetonide 67-73-2、67-73-2 Fluocinolone Acetonide. If these products fail to match your need, please contact us and we would like to provide relevant information.
Molecular Weight:
452.4999 Fluocinolone Acetonide is a corticosteroid that binds to the cytosolic glucocorticoid receptor.
Biological Activity
Fluocinolone acetonide(Flucort-N) is a corticosteroid that binds to the cytosolic glucocorticoid receptor. It is a corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching. It is a synthetic hydrocortisone derivative.
After binding the receptor the newly formed receptor-ligand complex translocates itself into the cell nucleus, where it binds to many glucocorticoid response elements (GRE) in the promoter region of the target genes.
The DNA bound receptor then interacts with basic transcription factors, causing the increase in expression of specific target genes. The anti-inflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory Proteins which, through inhibition arachidonic acid, control the biosynthesis of Prostaglandins and leukotrienes.
Contact us if you need more details on 67-73-2. We are ready to answer your questions on packaging, logistics, certification or any other aspects about Fluocinolone Acetonide 67-73-2、67-73-2 Fluocinolone Acetonide. If these products fail to match your need, please contact us and we would like to provide relevant information.
Product Categories : Endocrinology & Hormones > Glucocorticoid Receptor Inhibitor
Other Products
Hot Products
Astragaloside AChlortetracycline HCl 64-72-2Paclitaxel 33069-62-4Dexamethasone Acetate 1177-87-3Dinaciclib (SCH727965) 779353-01-4CHIR-124 405168-58-3Ro3280 1062243-51-9TAME 901-47-3CCG-1423 285986-88-110058-F4 403811-55-2Dabigatran (BIBR 953) 211914-51-1H 89 2HCl 130964-39-5T0901317 293754-55-9Aprepitant 170729-80-3Turofexorate Isopropyl (XL335) 629664-81-9BMS-378806 357263-13-9